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Dr. Tim Mosmann is Director of the human immunology center at the University of Rochester, with more than forty years of experience and major contributions in T cell mediated immunity
Expertise:
Prior Experience:
Award:
Education:
Expertise:
- Established a high-throughput proliferation and cytotoxicity assay for cytokines
- Used this assay to show that there were discrete patterns of cytokines produced by different T cell lines. This work expanded into the characterization of different functions and further cytokine patterns of Th1 and Th2 T cells
- Demonstrated that effector T cells were specialized for different functions, and laid the groundwork for more recent demonstrations of additional stable or semi-stable T cell subsets
- Led to the prediction of a cross-regulatory cytokine, resulting in the discovery of IL-10
- Worked on a subset of uncommitted precursor T memory cells that constitute a surprisingly large proportion of many human immune responses
- Is working on the objective analysis of flow cytometry data, collaborating on the development of algorithms that allow objective mining of the rich information contained in flow cytometry datasets
Prior Experience:
- Director of the Human Immunology Center, University of Rochester, USA (1998-present)
- Professor and Chair, Department of Immunology, University of Alberta, Canada (1990-1998)
- Research Scientist, DNAX then acquired by Schering plough, Palo Alto, USA (1982-1990)
- Assistant Professor, University of Alberta (1977-1982)
- Post-doctoral fellow, University of Glasgow (1975-1977)
- Post-doctoral fellow, Hospital for Sick Children, University of Toronto (1973-1975)
Award:
- Novartis Prize for Basic Immunology, 2013
- Pillar of Immunology, 2005, 2012, 2016
- Paul Ehrlich and Ludwig Darmstaedter Prize, 2008
- ASTECH award for Outstanding Leadership in Alberta Science, 1997
- William B. Coley Award, Cancer Research Institute (USA), 1997
- Fellow of the Royal Society of Canada, 1995
Education:
- Ph.D., microbiology, University of British Columbia, Canada (1973)
- BSc, microbiology, Rhodes University, USA (1969)
- BS, Chemistry and physiology, University of Natal, South Africa (1968)